SUPREM-MILK aims to provide concrete tools and propose customized and targeted solutions to support farmers of Egypt, Morocco, and Turkey to take a step towards a net zero carbon and greener and more circular farming. During the transition, the 3 forms of sustainability will be maximised and the resilience and self-sufficiency of the Mediterranean milk supply chain will be considered. In agreement with the specific challenges and scopes of the call, the main objectives are: 1 Preliminary inventory of the carbon cycle and characterization of sustainability of the milk supply chains studied. Life cycle assessment, sensors data, machine learning, remote sensing (Sentinel-2), and omics approaches will be used to evaluate the starting point of different scenarios and plan customized actions and solutions towards the desired direction(s). 2 Support the adoption and implementation of sustainable technologies, novel applications and best practices by local farmers. Transfer of knowledge, establishment of decision-support systems, definition of best practices/most recommended guidelines, and installation of open access digital applications/platforms will contribute to improve decision-making and informed choice of all stakeholders, especially those in underserved areas/condition with scarce access to technologies, e.g., smallholder farmers and women active in dairy. 3 End-point evaluation of the carbon balance, sustainability, self-sufficiency, and competitiveness of the milk supply chains considered. Multi-actor estimation of the impacts of the incorporated improvements; i.e. cost-benefit analysis, life cycle assessment, circularity level. All stakeholders of the chain will be considered: land (soil), animals, farmers, producers, and consumers. SUPREM-MILK will exploit an horizontal approach to customize and implement innovative tools that can rapidly improve nutrients circularity, self-sufficiency, and sustainability of Egyptian, Moroccan, and Turkish milk supply chain.