In this project, we will develop new chiral transition metal catalysts bearing N-heterocyclic carbene (NHC), cyclic alkyl amino carbenes (CAACs) ligands and other carbene ligands containing a sole axial chirality. In an original and unique manner, the complexes will be prepared from readily available achiral NHC precursors. Thus, the enantiopure complexes will be obtained by preparative chiral HPLC resolution which will provide access to both enantiomers with high optical purity (>99%). The design of the atropisomeric carbenes structures will be supported by DFT calculations which will be performed at an early stage. This project will tackle some fundamental aspects related to chirality including mechanistic aspects of carbene transmetalation, looking to understand the fate of the chiral information during this process. Beyond these fundamental studies, the aim is to create new series of efficient and inexpensive chiral catalysts in order to perform original enantioselective transformations.