High performance computing (HPC) allows scientists and industries to run large numerical application on huge data volumes. The HPC is a key factor in knowledge and innovation in many fields of industry and service, with high economic and social issues: aerospace, finance and business intelligence, energy and environment, chemicals and materials, medicine and biology , digital art and games, Web and social networks, ... Today, acquiring HPC supercomputer is very expensive, making HPC unreachable to SMIs / SMEs for their research and development. The CloudPower project results from the research and development projectXtremWeb lead INRIA, CNRS, University Paris XI and ENS Lyon. Its goal is to offer a low cost Cloud HPC service for small and medium-sized innovative companies. With CloudPower, companies and scientists will run their simulations to design and develop new products on a powerful, scalable, economical, reliable and secure infrastructure. The project will lead the creation of a new and innovative company operating the platform implemented in the framework of the ANR Emergence. CloudPower will leverage on the open-source software XtremWeb-HEP previously developed by the partners. The principle of the technology is to collect the under-exploited resources on the Internet (individual PCs, internet box, servers, data centers ...) to build a virtual supercomputer providing HPC services on demand. CloudPower will implement SaaS / PaaS portal for customers and develop extensions to allow commercial exploitation of unused resources. Building on the network of SMIs from the competitiveness clusters System@tic and LyonBiopole, we will implement scenarios and/or demonstrators which illustrate the ability of CloudPower to increase competitiveness, research and marketing of innovative SMEs.