Planet Earth faces unprecedented environmental changes that will affect all members of society. Arctic climate warming is more than twice the global rate and unpredictable extreme events cause major impacts on ecosystems and people. However, the Arctic atmospheric circulation causes extreme events and societal damage beyond the Arctic which need international research and monitoring to understand and predict. Furthermore, attitudes need to be changed throughout the world through outreach while the next generation needs to be equipped to live in a different world. INTERACT III innovates a pan-arctic network of 86 research stations in 16 northern countries to provide a fully integrated, advanced infrastructure now able to meaningfully address major societal challenges and provide services for 155 global and regional networks. Furthermore, the global reputation of INTERACT has attracted world-leading partners and enterprises to participate in reducing the impacts of hazardous change while maximizing the opportunities arising from new technologies. Specifically, INTERACT III provides comprehensive coordination of 64 partners and 86 research stations. The station managers design best practices to ensure excellent research, monitoring, education and outreach. INTERACT III builds on an extremely successful transnational access program that has already populated the Arctic with 900 researchers to further provide excellent science while reducing the environmental footprints of researchers through improving remote and virtual access. The access transnationality ensures new collaborations, innovative science and science diplomacy at a time of heightened geopolitical tensions. Station managers, transnational access and joint research activities cooperate to address major societal challenges in a fully integrated infrastructure while their data and understanding are made globally available through exceptional outreach and education and policy briefings to decision makers.