Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

The project is focussed on the use of ammonia as a carbon-free fuel, to fully decouple the supply and demand of electricity from fluctuating renewable energy sources. A small scale demonstrator will be designed and assembled, to evaluate the performance and scaleability of a system that accepts intermittent energy and delivers reliable matched base load electricity to meet demand. The key components of this local configuration are an “agile synthesis unit” which produces ammonia, a generator and internal combustion engine, suitable to use the stored ammonia to generate electricity on demand.

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

Cardiac Resynchronisation Therapy (CRT) has been shown to be a safe and effective treatment option in patients with advanced drug-refractory Heart Failure (HF), systolic dysfunction and ventricular dyssynchrony. However, up to one-third of patients implanted with a CRT device show no improvement in symptoms and up to half of patients show no improvement in cardiac function. These non-responders are a strong burden to healthcare systems by causing considerable unnecessary costs, e.g. for devices, implantations, recurring follow-up visits as well as hospitalisations for acute HF decompensation The aim of this project is to develop a single platform which integrates all stages of the CRT pipeline, referred to as the “Guide CRT”, to improve response rate. The main components of this include MR clinical imaging protocols dedicated to HF patients, tailored image processing tools (segmentation of the heart morphology, myocardial scar and coronary sinus, as well as analysis of left ventricle (LV) wall motion), fused visualisation for improved patient selection and planning of LV lead placement, and the image-based guidance technologies to support CRT device implantation. Guide CRT will be evaluated on a cohort of 50 patients. Through the proposed joint efforts between leaders in their respective industrial, academic and clinical fields, we aim to demonstrate that integrating comprehensive multimodal imaging data and tools can help to provide answers to the great challenges of CRT, namely identification of patients who are likely to respond and guiding LV lead placement to maximise this reponse.

It is understood that wireless communication links between road vehicles and infrastructure will be commonplace in the near future. Such links will lead to the availability of a rich new data source potentially containing real time position and speed data (among others) for some or all vehicles on the UK road network. This creates business opportunities to develop tools that can employ this “localization probe data”, alongside existing sources, in applications. An application of particular interest is Urban Traffic Control (UTC). The technical objective of this research project is to create a city centre sized microscopic traffic simulation model. Measurement systems (including localization probes) will be simulated. Thus the simulator becomes a proving ground for the development of novel UTC techniques that employ these data. This project will output techniques and algorithms for the next generation of UTC systems. Also output will be processing and visualization techniques that can present a human traffic controller with the state of the traffic network. Finally, general processing and visualisation tools for 3rd party (non UTC) applications will be produced.