The PROSPECTS 5.0 project aims to promote the adoption of Industry 5.0 principles, such as human centricity, sustainability, and resiliency, and facilitate the transition to Industry 5.0 for SMEs, start-ups, and scale-ups in various industries. The project intends to achieve its objectives by providing reports, guidelines, measurement tools, and a collaborative platform. To provide real-world examples, the project will analyse 14 use cases from different European Union countries and 6 different industries, covering various types of manufacturing, service providing, education, energy, aviation transport, and automotive. The selected industrial sectors are significant drivers for the adoption of Industry 5.0 and are crucial to the European economy. The use cases from these sectors will ensure a focused and effective transition to Industry 5.0 in Europe. PROSPECTS 5.0 results are expected to encourage collaboration between different entities, including companies, universities, research centres, and government agencies, to co-create new solutions and innovations, improve the skills and mindsets of individuals regarding Industry 5.0, and study pilot projects to test, validate, and measure the impact of Industry 5.0 on various operations, employees, customers, and the environment. Additionally, PROSPECTS 5.0 will raise awareness of Industry 5.0 through workshops, seminars/webinars, and collaborative online platforms and web applications showcasing successful case studies, best practices, challenges, and the latest trends and opportunities of this transition. PROSPECTS5.0 is relevant to the worker Horizon Europe Cluster 4 (Digital, Industry, Space) specifically to destination 6 “A human-centred and ethical development of digital and industrial technologies since the project results will lead to a more inclusive and sustainable EU Industry, and indirectly, the project findings will facilitate the understanding of the required skills needed to support the twin transition.