The mission of FUROID is to enable animal-free production of hair (humans), fur (endangered animals) or wool (sheep). The key innovation is the development of continuous and scalable technology, enabling the end of using living animals as a source of fur and wool and dominating the market by 2030. Specifically, we will focus on the development of engineered living fur (ELF), The mission of FUROID is to enable animal-free production of hair (humans), fur (endangered animals) or wool (sheep). The key innovation is the development of continuous and scalable technology, enabling the end of using living animals as a source of fur and wool and dominating the market by 2030. The fundamental innovation will be reached by using a combination of nanostructured scaffolds (RESPILON), hair/wool/fur organoids (GENEUS), and automated biofabrication technologies (BIOFABICS). The ambition of the project is to make significant steps to development of HLM products will deliver set of unprecedent properties: • Animal free-production of fur (ELF) and wool (ELW) without environmental, biodiversity and ethical concerns. • Gene-encoded traceability system endangered species unnoticed, uncontrolled and unpunished endangered species poaching. • Novel vacuum-assisted 3D printing technology overcoming speed of SoA 3D bioprinters • Continuous manufacturing using an automated production system • DBTL platform for rational design and product optimization. • Living human hair follicles (ELH) for transplantation and treatment alopecia as medical and psychological problem. • Fur and wool textiles for apparel industry in rolls without size limitation delivering unprecedent properties. • Improved properties of engineered fur/wool textiles due to nanofiber membranes with regulated water permeability. The project will strengthen the portfolio of ELMs by developing scalable and generalizable technology for forming textured materials in roll-to-roll process from mammalian cells.

ESCULAPE project is targeted to building a strong interdisciplinary partnership in order to support joint research and innovative activities in the fields of biomaterials, polymer science, nanotechnology, tissue engineering, microbiology and medicine with the aim to explore development and implementation of new medical engineering solutions for regenerative medicine and wearable electronics. The project will offer novel solutions (from the manufacturing stage to exploitation strategies) using MXenes, a new class of two dimensional (2D) materials consisting of transition metal carbides/carbonitrides. MXenes will be employed to modify properties and qualities of porous 3D electrospun nanoscaffolds, which will be used in tissue engineering for regenerative biomedicine and development of wearable electronics on both woven and non-woven fabrics. The main goal of the ESCULAPE project is to build a new training partnership to develop innovative strategies to achieve advanced biomaterials with target-oriented properties (electrical conductivity, biocompatibility etc.) that will be able to deliver specific features for regeneration of heart and nerve tissues, regulation of homeostasis in iPSCs, as well as in development of wearable electronics. Interdisciplinary and inter-sectoral secondments will be the main tool for project realization with the aim of strengthening research, training, communication and networking capacities of participant organizations and knowledge transfer from academia to industry and vice versa. Proposed research and training goals will lead to enhance research and transferable skills of the ESRs, as well as their competences with the aim of improving competitive employability and career prospects in both academic and industrial sectors. Public dissemination of new research results will increase the awareness of general society on the role of researchers and research infrastructure in establishing the EU as a world leading R&I force.