Healthcare fragmentation is a main cause for delay in cancer diagnosis and treatment, contributing to high and steadily increasing mortality rates in Latin America(LA), particularly among disadvantaged populations. Building on Equity-LA I (GA223123) and II (GA305197), this research focuses on integrated care interventions, which have proven effective at improving early diagnosis of cancer, mostly in HIC, and are also promoted by national cancer plans in LA, but limitedly implemented or evaluated. The objective is to evaluate the contextual effectiveness of scaling-up a multicomponent integrated care intervention to improve early diagnosis of frequent cancers in healthcare networks of Chile, Colombia and Ecuador. Method: This participatory, interdisciplinary and mix-methods implementation research is two-pronged: a) a quasi-experimental design (controlled before and after) with an intervention and a control healthcare network; b) a case study design. Focussing on the most vulnerable socioeconomic population, it develops in four phases: 1) analysis of delays, related factors and contextual barriers to early diagnosis (base-line); 2) adaptation and scaling-up of the intervention (PC training, fast-track referral pathway and patient information, adapting available ICT tools) in real life; 3) intra-country evaluation of intervention; 4) cross-country analysis. ICT tools will be also adopted in research activities as needed in a Covid-19 on-going or post- pandemic context. Relevance: EquityCancer-LA contributes to H2020 call objectives advancing cancer control policies by generating: 1) robust evidence on contextual effectiveness and costs-effectiveness of an affordable, tailored intervention to reduce diagnostic delays; and a validated strategy for its large-scale implementation in LA and LMICs; 2) novel data on delays and key barriers and facilitators to early diagnosis and inequalities in access; 3) e-tools to improve clinical practice and research on early diagnosis.

suHCO will address the common challenge of transitioning the healthcare sector to sustainability by procuring a horizontal digital planning and execution-driven system. Suppliers will be requested to embrace and integrate multiple technologies and the latest research in AI, platform, behavioural and economic sciences. The Buyers Group represents three major markets (ES, IT, UK) and the full diversity of EU health care systems (central procurement, hospitals, care homes, surgeries, home care etc.). Leading research organisations on sustainability, logistics and PCPs in healthcare and digital innovation are supporting. The group has already started to recruit a Follower Network. The suHCO-system is to empower all types of Health Care Organisations(HCOs) and their staff to design, plan, implement and act sustainably more easily, quickly and widely. It is to cover four areas of need: 1) to help HCOs and users to understand the growing number of vertical sustainable practices and solutions already available (information); 2) to develop and implement an effective sustainability strategy based on opportunities for impact given the local circumstances (operation); 3) to facilitate all necessary interactions with stakeholders such as health decision-makers and product and service providers (organisation); 4) to change the mindset and upskill administration, end-users and SMEs. The system will adopt to the local regulatory requirements.It will be scalable and can implemented by individual HCOs or entire health systems. suHCO will be modular allowing specialised software companies to embed components into existing solutions. Uptake will rapidly grow the market for sustainable solutions and provide new opportunities for innovative SMEs and start-ups. Advancing the sustainable transition of healthcare will reduce the need for virgin materials, reduce waste and pollution. suHCO advances the One Health Approach through direct impact and high replicability in developing countries.