The performances of ground- and airborne transport vehicles, wind turbines, rotating machinery, combustors and many other configurations are strongly affected by flow separation and consequently benefit from efficient separation control. Further performance enhancements by passive and active devices are requested by industry. This proposal targets a model-based separation control strategy working robustly in experiment for a range of operating conditions. Focus is placed on nominally 2D configurations at different Reynolds numbers. The flow control demonstrators cover the range from laminar to turbulent separation, including a low Reynolds-number smooth backward facing step (Poitiers, water tunnel), a similar configuration at medium Reynolds-number (Orleans, wind tunnel) and a high Reynolds number ramp (Lille, wind tunnel). The physical understanding is augmented by reduced-order models (ROM) from experimental data (Poitiers), URANS simulations (Orleans), and LES computations (Lille). The flow is manipulated with passive vortex generators and active control from periodic excitation to closed-loop design using ROM. We import and adapt promising strategies having worked in other experiments. The breadth of control plants will enable the proposal consortium to distil the key actuation mechanisms and arrive at good practices for robust separation control for various conditions. As one educational benefit, the consortium aims at involving students from the International Master of Turbulence program (Lille, Poitiers). On a French national level, the studies shall define experimental benchmark demonstrators for more refined modelling and control strategies, to be maintained and presented in the GDR 2502.