The SAUST project aims to revolutionize aviation security and customs inspections by providing a rapid, non-intrusive and efficient alternative for vapor baggage screening at airports, being the first attempt before the Explosive Vapour Detection (EVD) European Civil Aviation Conference (ECAC) Standard 2 and 3 (hold baggage and cabin baggage) implementation, but with a high focus on drug detection at airport arrivals where the 85% of the drugs are seized in Europe providing new technology to police and customs authorities to increase both the inspection rate, efficiency and drug database including NPS (New Psychoactive Substances). SAUST’s primary objective is to adapt an existing EVD methodology, previously tested under different conditions, mainly explosive screening of air cargo, to create a smaller, more affordable, and faster solution for luggage inspection since the requirements are totally different. The consortium is determined to address this issue through collaboration with industry, mainly SMEs, and police agents as experts who possess an in-depth understanding of the genuine requirements and constraints in customs and airport security. SAUST will develop a versatile, cost-effective, and expeditious screening technology, adapted to luggage screening, that enhances detection capabilities for a wide range of substances, including drugs and explosives, and other illicit substances like tobacco and drug precursors among many others. The ultimate goal is to develop a Technological Readiness Level (TRL) 7 operational prototype, which will bridge critical security and operational gaps in the current screening processes. In addition, the project will provide an analysis of the different scanning options for luggage in order to ensure the airport logistics without disrupting the flow. SAUST border impact has the potential to revolutionize customs inspections, providing technology to activities that currently are mainly done using traditional or manual techniques.