"New technologies and scientific developments over the recent years have radically changed the landscape in health and education, bringing benefits that were unimaginable until recently but also problems for workers, teachers and students. Many systems, devices and techniques used in the daily work are becoming increasingly complex and automated, requiring specific training or, at best, skill updating for health professionals. In the educational area, due to the high cost of acquisition of many devices used in hospitals, their complexity and their hazard (for example, in the field of radiological protection), students in Health Education Training Centres cannot experience how these devices work and neither can they see the real environment they will have to face in the future. The training of these students is drifting away from the reality that they will encounter and this is a problem both for students and for biomedical companies themselves.In this context, the general objectives of the project ""Extended reality in biomedical environments"" are: to bring closer together the reality of biomedical companies and health training centres through mixed reality, augmented reality and virtual reality and to improve the knowledge acquisition of our Students in health care training. To solve the problems described above and to take advantage of the possibilities of extended reality, the project proposes four lines of work that will be materialized in 4 products:1. Remote training or Tele-training: a video conference with virtual elements (computer graphics, images, etc.) in which a speaker from a Specialized Biomedical Research Center explains a technique or a device in a biomedical environment to our students, who are physically present at the educational center.
2. Virtual rendering of professional biomedical environments: the aim is to build virtual working environments faithfully and quickly using BIM technology that can be used on different platforms (mobile, tablet, PC...) or even 3D printing.3. Holographic simulators: in this line, the aim is to create virtual simulators of biomedical devices using virtual and mixed reality that have functionalities similar to those of a real device, with the possibilities of enriching the experience with didactic elements.4. Holographic tutorials: this is the creation of devices tutorials using holograms and multimedia elements that help students understand and manage them.In the development of the project, which lasts 36 months, 6 public and private institutions are working together:- CIFP Los Gladiolos (Spain): Vocational Training Centre specialized in health system professions. It is the coordinating centre of the project.- Kauno Kolegija University (Lithuania): working closely with CIFP Los Gladiolos, it is in charge of the methodological proposal of the project.- University of La Laguna (Spain): together with the University of Videzme, it is responsible for coordinating the digital production of the resources (professional environments and simulators) and for providing technical support for tele-training and holographic tutorials.- University of Vidzeme (Latvia): it is a university with great prestige and experience in European projects and technological innovation.- The company Geoavance (Spain): carries out the scanning of professional environments and its BIM modeling.- The Basque Health Service. Osakidetza (Spain): in collaboration with Bioaraba - OSI Araba - Health Research Institute, it is responsible for organizing the scans to be carried out and for providing quality and rigorous information on the radiological protection equipment selected.To carry out all this, the work will be coordinated on the basis of the needs detected in the health training centres (Los Gladiolos and Kauno Kolegija). With these needs and with the advice of the Basque Health Service ,Osakidetza, proposals will be made for content and teaching methods that will be materialised in educational resources created or supported by the University of La Laguna, University of Vidzeme and Geoavance.The expected results are the improvement in the training for students, closing the reality gap between training centres and biomedical companies, a greater interest of companies in the work carried out by educational centres and finally the creation of high quality resources for teachers.In the long term, it is expected that these 4 products will be transferred to other European educational centres and will be further enhanced in order to improve their main objectives: to bring the reality of the biomedical companies even closer to the educational centres and to improve training for thousands of students."

Over 50m people suffer from multimorbidity (PMM) in Europe. Recent reviews find that PMM experience a range of system and professional-related issues with care delivery. In part, this is because current investments in process-based delivery means delivering healthcare within single diagnoses tracks/silos. For PMMs this does not reflect real-world conditions. No technology is available today that enables the specific care, treatment, administration and support needed for this target group. Breakthrough solutions will classify the individual according to their co/multimorbidities and medications. But this needs to be developed in close dialogue between PMM, care providers and industry sectors based upon a strong demand driven approach in a PCP. Accordingly, the CareMatrix Buyers Group (SE, NO, ES) challenge the market to develop innovative technology that enables more predictive care and support benefits for PMM. This is achieved with 6 project objectives summarised as PCP: stakeholder engagement, roadmap, Call, implementation, next steps and; profiling and outreach via IFIC. The methodology can be summarised as PCP: framing actions (PCP preparation, use of UCD principles and practice); implementation actions (Phases 1-3 contract management, support, evaluation and testing) and Market Preparation actions (business development support for Phase 3 suppliers, standards, initial PPI preparation). Direct benefits include: • 20% reduction in time spent for visits to care facilities • Improvements from baseline in at least 75% of aspects of care as identified using PREM surveys • 50% fewer patient data-related incidents (increased patient safety) between organizations • No of clinical errors reduced by 30%; Underpinning the CareMatrix solution(s) with integrated innovation (supportive policy priorities, organisational and social innovations) will optimise the potential of those solutions to produce savings of 10% in health care expenditure for PMM.

• CONTEXT Professional mobility has become an inherent feature of today’s global world. Mobility of the nursing profession as well as mobility in patient populations (Buchan et al. 2014; Buchan, et al. 2017; United Nations 2018) has led to cultural heterogeneity and language discordance (Stilwell et al. 2004). • OBJECTIVESIn order to respond to the growing intercultural communication needs, TraINErS –Training Intercultural Nursing Educators and Students–develops a theoretically sound (blended) training program consisting of internationally tested, validated as well as accredited online/mobile materials and longitudinal online support to train educators involved in the development of nursing students' intercultural competences and skills. TraINErS will enhance encounters with diverse patient populations as well as prepare nurses to be(come) mobile professionals integrating in new socio-cultural contexts. TraINErS will define a profile with intercultural competences and skills for educators as well as students to foster intercultural communication in healthcare and develop a tool to evaluate intercultural communication growth. Thus, the program will have an immediate effect on nursing students before/during/after an international exchange, but also address intercultural competence-at-home. • PARTICIPANTSThe development of profile, blended program and evaluation tool will culminate in two training activities (in the east and in the north of the EU) where educators and nursing students (N=140) will collaboratively enhance their intercultural communication. • ACTIVITIESTraINErS will develop innovative learning opportunities in intercultural nursing communication by supporting nursing educators as well as students in acquiring and further developing the required skills and competences to become interculturally proficient professionals. TraINErS will first draw a reliable and validated profile of the Intercultural Nursing Educator (INE), since a study of the literature has shown that such a profile is not available and training is often not theoretically supported. The profile will be converted in an evaluative online/mobile instrument for educators to measure their own intercultural sensitivity growth and learning gain while undergoing blended training. Authentic and relevant materials will be responsibly designed and presented as part of a blended multimodal training program for intercultural nursing communication with online support culminating in an in-service training activity where educators will complete their earlier started online training and immediately apply it in sessions with international nursing students. By explicitly focusing on the intercultural communication competences in nursing the project is in line with the increasingly globalised profile of the profession and will prepare interculturally competent (pre-)professionals for the future. Every step of the development process will be evaluated on a process and product level.• RESULTS and IMPACTAs an online/mobile tool and program TraINErS empowers professionals to autonomously improve their communication skills in an additional culture. The online cases will contain a test module, which will be scored. Accreditation will be put in place. STUDENT nurses will -develop awareness of their intercultural sensitivity/growth and articulate how this may affect their nursing practice -compare/contrast the cultural identity in the training with their own-apply principles of intercultural nursing communication to nursing practice in different international case scenarios in the training -recognize detrimental effects of ethnocentrism, cultural stereotyping, prejudice and cultural imposition-identify health inequalities and support plans to improve them -use culturally sensitive (non-)verbal communication in nursing care in cases during blended training -develop their language (the program is English-medium taught), gain foreign language insights and interpersonal and critical thinking skills. The EDUCATORS will-identify their own cultural sensitivity and gain-engage in learning (about) intercultural communication in nursing-engage in the teaching materials and approach to facilitate intercultural nursing communication-apply teaching/learning strategies to promote their own understanding of the learning trajectory-apply good practice in intercultural nursing communication through micro-teaching during the training activity. • LONG term benefit and impact:TraINErS introduces tailor-made communication support into the vocational training system of highly skilled professionals;-raises awareness about intercultural communication in clinical settings;-fosters intercultural nursing communication since professionals are provided with a tool to progress from less cultural sensitivity to a level where they will be able to operate as interculturally competent professionals;-enhances intercultural healthcare communication.

Clinical need: 10% of the population worldwide is affected by chronic kidney disease (CKD) and millions die each year because they do not have access to treatment. Giving global shortage of kidney donors, the vast majority of patients rely on hemodialysis (HD). Over 2.6M people worldwide currently receive HD to stay alive, yet this number may only represent 10% of people needing treatment. Solution: Up to 70% of current arteriovenous grafts (AVG) fail in the first year after implantation. This is primarily due to thrombosis, luminal scar formation, and infection. In our ground-breaking new AVG, biomimicking zwitterions prevent thrombosis, drug delivery prevents scar formation and infection, and an ECM coating ensures fast tissue integration allowing early HD. Smart: TELEGRAFT comprises two diagnostic tools to monitor and prevent device complication. Pressure transmitters are used to monitor blood flow and optical sensors to detect inflammation and infections. The data is processed by AI machine learning models and displayed in an easy to understand dashboard for healthcare professionals. The data allows online telemonitoring and consultations by remote healthcare professionals. This makes home dialysis safe for patients, even in areas with poor infrastructure, where patients live far from HD clinics. Surgical implantation: The TELEGRAFT system will be demonstrated in an operational environment through a 2-stage randomized clinical trial enrolling 60 patients at 5 hospitals across Europe and through a home HD field study. Resource constrained setting: (1) In low and middle income countries, TELEGRAFT will substitute complicated and expensive kidney transplantation and allow simpler and cheap implantation of AVG for HD. (2) TELEGRAFT is the only solution with diagnostic tools allowing real-time online detection and remote monitoring of complications and device failure. This allows transition from HD at the hospital to the resource constrained home setting.

C3-Cloud will establish an ICT infrastructure enabling a collaborative care and cure cloud to enable continuous coordination of patient-centred care activities by a multidisciplinary care team and patients/informal care givers. A Personalised Care Plan Development Platform will allow, for the first time, collaborative creation and execution of personalised care plans for multi-morbid patients through systematic and semi-automatic reconciliation of clinical guidelines, with the help of Decision Support Modules for risk prediction and stratification, recommendation reconciliation, poly-pharmacy management and goal setting. Fusion of multimodal patient and provider data will be achieved via C3-Cloud Interoperability Middleware for seamless integration with existing information systems. An Integrated Terminology Server with advanced semantic functions will enable meaningful analysis of multimodal data and clinical rules. Active patient involvement and treatment adherence will be achieved through a Patient Empowerment Platform ensuring patient needs are respected in decision making and taking into account preferences and psychosocial aspects. Co-design and 4-layered multi-method multi-stakeholder evaluation will lead to a user friendly solution. To demonstrate feasibility, pilot studies will focus on diabetes, heart failure, renal failure, depression in different comorbidity combinations. Pilots will operate for 15 months in 3 European regions with diverse health and social care systems and ICT landscape, which will allow for strengthening the evidence base on health outcomes and efficiency gains. C3-Cloud adaptive patient pathways and organisational models validated by patient organisations and a clinical reference group, change management and training guidelines will be shared with the European community. Commercial exploitation of C3-Cloud integrated care solutions will be facilitated through an Industry Vendor Forum and commercial EHR/PHR products of 3 leading SMEs.