Rural BioReFarmeries brings together farmers, industries and other partners across Europe, to demonstrate a farmer-centred bioeconomy model aimed at maximizing the potential of Europe’s vast grasslands. The project will demonstrate a novel small-scale, decentralized, rural green biorefinery value chain, which addresses the limitations of existing green biorefineries. This small-scale decentralized model places farmers at the centre of the biomass value creation close to their farms, allowing them to co-produce inputs for their farms, with additional high value-added intermediates and products, which will be further developed in collaboration with centralized facilities and downstream industry partners. The model provides a practical implementation of the bioeconomy among a large farmer cohort and builds on the existing farm enterprises and cooperative structures of our partners, enabling collaboration, scale-up, market access, and building synergies across primary and industrial sectors. The project advances state-of-the-art for green biorefinery in terms of operational model, logistics, processing, product development and assessment methods, which collectively deliver a more sustainable and profitable model for farmers and rural communities. The model will serve as a blueprint for farmers to sustainably diversify into the bioeconomy, reducing their farm emissions while creating new products which displace unsustainable alternatives in a range of agri-food markets. Rural BioReFarmeries model will be replicated to diverse regions of Europe, supported by the development of inclusive business models and hands-on training among multi-actor groups and communities in regions of high potential. The project represents a highly replicable model for Europe’s abundant grasslands, helping farmers to deal with sustainability and profitability challenges while helping rural communities to become more resilient while realizing the potential of their local bioresources.