The evolution of rapid auxin signalling pathway In plants, the hormone auxin can trigger fast cellular responses. These respones are evolutionary conserved, yet little is known about how they are generated. This project will compare fast auxin responses in distinct plant species using genetics and biochemistry to identify the key components that generate these responses.

Antimicrobial resistance (AMR) is a major threat for animal and public health and recognized by Heads of State in the General Assembly of the United Nations as a major issue on global scale. To contain AMR, antimicrobial usage (AMU) should be reduced as this is considered to be the main driver of selection for resistant bacteria. Furthermore, the veterinary use of (highly prioritized) critically important antimicrobials for human medicine should be reduced as much as possible and replaced by less important antimicrobials for human medicine. Preliminary data collected by consortium partners, showed considerable overuse of antimicrobials in the Indonesian poultry production. Scientific research is needed to support an evidence-based transition towards a sustainable poultry production chain with responsible use of antimicrobials. The research questions are i) why, what and how much antimicrobials are used in broiler production in Indonesia, ii) what alternatives for AMU are available iii) is it possible to reduce AMU by introducing tailor made on-farm intervention strategies. The parameters to be measured are reduction in AMU and the change in AMR levels on farms. One of the results of this project will be the development of a ‘best practice’ document to be used (inter)nationally by stakeholders and scientific publications to share the results with the scientific community. The consortium consists of research organisations, a commercial partner and 4 supporting organisations with strong links with the broiler sector in Indonesia. Two stakeholder meetings will be part of this project to ensure close involvement in the development of the intervention and in the end phase to communicate results and best practices to end-users. Several elements of capacity building are one of the pillars of the project. This project contributes to a safe and sustainable poultry food chain in Indonesia and reduces the risks of resistant bacteria for humans.

In The Netherlands “the land of water” the ecological quality of ponds, ditches, wetlands and lakes is severely degraded due to escalating and interacting anthropogenic pressures including pollutants and climate change. SEFAP unites leading Dutch freshwater experimentalists, infrastructures and data scientists to provide a step forward in collaborative science and inland water ecology. By conducting experiments in SMART-enabled replicated mini-lake ecosystems, SEFAP will enable the future of our waters to be experimentally created and tested. In combination, the technical innovation and community-building of Dutch aquatic experimentalists will strengthen the ability to predict and mitigate undesirable futures in aquatic ecosystems.

With an increasing global urbanization, demands on the livelihood of cities are rising swiftly. In the conventional urban growth, biodiversity is often constrained, separation of functions leads to inefficient resource use, impact of climate change becomes extreme and human health is increasingly endangered. Green infrastructure (GI, e.g. green roofs, parks) in cities may simultaneously supply multiple functions that contributes to solve these issues. The challenge is how to accommodate and harmonise these possibly synergising or competing functions of GI in current and future urban landscape. Here, transdisciplinary learning[14] will be used to co-create the planning and design of the multi-functioning of GI in cities. Building from our experiences in Xiamen, Breda and Nieuwegein, we will develop and evaluate such multi-functional designs for these cities. We hypothesize that learning among multiple disciplines and cities are the two keys to unlock the potential of multi-functioning of GI. In this research we aim at operationalizing this learning process via (1) co-creation of a GI planning and evaluation tool, MultiGreen, to stimulate and distil the transdisciplinary learning for multi-functioning of GI and (2) participatory-based application of MultiGreen in selected case cities to facilitate learning among stakeholders so as cities. We start with, but not limited to, integrating three main GI functions: the circular food provision, climate adaptation, and biodiversity restoration; different GI approaches like urban farm, green roofs or wadi are thus considered. Then, a GIS-based building stock model is connected to an agent-based model to analyse the potential of ecological and social-economic benefits for accommodating different GI approaches. At last, a geo-spatial module matching the GI provision of multi-functioning and local demands will be developed and applied via a participatory approach in different case cities. Thus MultiGreen will enable the future designs of multi-functional GI to maximize the livelihood cities.

Enteric viruses from sewage overflows into water catchments threaten public health through food production and recreational activities. Despite wastewater treatment and water quality monitoring, viral contamination of food still occurs in Europe, impacting consumers health and food producers economically. Shellfish filter large amounts of water, making norovirus contamination a major cause of foodborne outbreaks. While rainfall plays a role, the impact of extreme weather events remains unclear. This project aims to ensure safe and sustainable water use, particularly in shellfish production, by improving understanding of viral contamination and developing an early-warning tool to mitigate risks during extreme hydroclimatic events.