Powered by OpenAIRE graph

UNIV PIERRE ET MARIE CURIE

Country: France

UNIV PIERRE ET MARIE CURIE

9 Projects, page 1 of 2
  • Funder: French National Research Agency (ANR) Project Code: ANR-06-PETB-0003
    Funder Contribution: 747,419 EUR

    DNA vaccines are considered among the most promising novel genetic vaccines against infectious diseases, and may have a great economical value in the future. However, it appears that DNA vaccination typically induces cellular immunity but rarely or inefficiently neutralising antibodies that often play a major role in protection against viruses; in addition, although efficient vaccination has been obtained in mice using 1st generation DNA vaccines, these results were not achieved in human vaccination. The aim of this project is to combine the 2nd generation DNA vaccine technologies independently developed by the two SMEs, to generate optimized 3rd generation efficient DNA vaccines (hence DV 3. The novel DNA vaccination technology for priming and boosting immune response will combine:1. the auxo-GTU technology that allows strong and long term expression of the antigens using vectors carrying segregation/partitioning function of the Bovine papillomavirus type 1 (Krohn et al., 2005); 2. the plasmo-VLP technology that allow to express the immunogens within and onto virus-like-particles (DNA vaccines encoding retrovirus-based virus-like particles induce efficient immune responses without adjuvant. Bellier B et al, Vaccine. 2005 Dec.) 3. optimised delivery of the vector

    more_vert
  • Funder: French National Research Agency (ANR) Project Code: ANR-05-RIAM-0001
    Funder Contribution: 543,592 EUR
    more_vert
  • Funder: French National Research Agency (ANR) Project Code: ANR-05-RIAM-0004
    Funder Contribution: 344,636 EUR
    more_vert
  • Funder: French National Research Agency (ANR) Project Code: ANR-05-RIAM-0017
    Funder Contribution: 534,547 EUR
    more_vert
  • Funder: French National Research Agency (ANR) Project Code: ANR-05-RIAM-0015
    Funder Contribution: 396,329 EUR
    more_vert
  • chevron_left
  • 1
  • 2
  • chevron_right

Do the share buttons not appear? Please make sure, any blocking addon is disabled, and then reload the page.

Content report
No reports available
Funder report
No option selected
arrow_drop_down

Do you wish to download a CSV file? Note that this process may take a while.

There was an error in csv downloading. Please try again later.