Evolution over the eons has made Nature a treasure trove of clever solutions to sustainability, resilience, and ways to efficiently utilize scarce resources. The Centre for Nature Inspired Engineering will draw lessons from nature to engineer innovative solutions to our grand challenges in energy, water, materials, health, and living space. Rather than imitating nature out of context or succumbing to superficial analogies, research at the Centre will take a decidedly scientific approach to uncover fundamental mechanisms underlying desirable traits, and apply these mechanisms to design and synthesise artificial systems that hereby borrow the traits of the natural model. The Centre will initially focus on three key mechanisms, as they are so prevalent in nature, amenable to practical implementation, and are expected to have transformational impact on urgent issues in sustainability and scalable manufacturing. These mechanisms are: (T1) "Hierarchical Transport Networks": the way nature bridges microscopic to macroscopic length scales in order to preserve the intricate microscopic or cellular function throughout (as in trees, lungs and the circulatory system); (T2) "Force Balancing": the balanced use of fundamental forces, e.g., electrostatic attraction/repulsion and geometrical confinement in microscopic spaces (as in protein channels in cell membranes, which trump artificial membranes in selective, high-permeation separation performance); and (T3) "Dynamic Self-Organisation": the creation of robust, adaptive and self-healing communities thanks to collective cooperation and emergence of complex structures out of much simpler individual components (as in bacterial communities and in biochemical cycles). Such nature-inspired, rather than narrowly biomimetic approach, allows us to marry advanced manufacturing capabilities and access to non-physiological conditions, with nature's versatile mechanisms that have been remarkably little employed in a rational, bespoke manner. High-performance computing and experimentation now allow us to unravel fundamental mechanisms, from the atomic to the macroscopic, in an unprecedented way, providing the required information to transcend empiricism, and guide practical realisations of nature-inspired designs. In first instance, three examples will be developed to validate each of the aforementioned natural mechanisms, and simultaneously apply them to problems of immediate relevance that tie in to the Grand Challenges in energy, water, materials and scalable manufacturing. These are: (1) robust, high-performance fuel cells with greatly reduced amount of precious catalyst, by using a lung-inspired architecture; (2) membranes for water desalination inspired by the mechanism of biological cell membranes; (3) high-performance functional materials, resp. architectural design (cities, buildings), informed by agent-based modelling on bacteria-inspired, resp. human communities, to identify roads to robust, adaptive complex systems. To meet these ambitious goals, the Centre assembles an interdisciplinary team of experts, from chemical and biochemical engineering, to computer science, architecture, materials, chemistry and genetics. The Centre researchers collaborate with, and seek advice from industrial partners from a wide range of industries, which accelerates practical implementation. The Centre has an open, outward looking mentality, inviting broader collaboration beyond the core at UCL. It will devote significant resources to explore the use of the validated nature-inspired mechanisms to other applications, and extend investigation to other natural mechanisms that may inform solutions to problems in sustainability and scalable manufacturing.

We propose an End Use Energy Demand (EUED) Centre focused on Energy Epidemiology to be located at the multidisciplinary UCL Energy Institute (UCL-Energy), which undertakes research on energy demand and energy systems. Energy Epidemiology uses data and modelling to study energy use in the real world, with the aim of understanding the interactions of policy, technology, infrastructure, people and culture. The Centre for Energy Epidemiology (CEE) will: undertake primary data collection; advise on data collection; provide secure and ethical curation of a wealth of administrative, commercial and research data; link, develop and use innovative research methods; and support a structured research programme on energy demand intended to achieve a major reduction in UK carbon emissions. CEE will provide key research and policy insights at city, regional, national and international levels. It will support UK academics, policymakers and industry to research energy demand, by providing a cost-effective, secure and ethical bureau service for energy and related data. It will work closely with the new cross-government Energy Efficiency Deployment Office (EEDO) of DECC, the Energy Saving Trust, UK Energy Research Centre (UKERC) and the new Open Data Institute (ODI) to marshal and maximise the value of existing and very large future sources of energy-related data ('big data'), ensuring the greatest impact for evidence-based energy demand research. The Centre will initiate and be a key player in an international network of energy epidemiologists, sharing research methods and undertaking cross-cultural comparisons of policies and technologies to reduce energy demand and to help the UK to meet its carbon targets. UCL-Energy: - has a clear focus on energy demand and its interaction with energy supply systems - this has been the core focus of UCL-Energy since its launch, with full UCL support, 35 months ago. - is multi- and interdisciplinary with lawyers, economists, social scientists, engineers, physicists, psychologists, architects, mathematicians and policy analysts co-located in open plan offices facilitating collaborative work. It has successfully worked with researchers from anthropology, English literature and history on energy demand problems. - makes an impact by supporting policy makers and industry to both set and achieve UK carbon targets. Examples of such support include the Green Deal, CCC budgets, smart meter rollout, and the development of products for reducing energy demand. UCL-Energy is the only university centre that has officially advised DECC's new EEDO, whose focus is squarely on EUED. - undertakes research of the highest quality; its staff were recognised as "world leading" by two successive EPSRC Platform Grant reviews. Roughly half its staff were submitted in the Built Environment UoA (30), for which UCL received the highest percentage (35%) of internationally leading staff (4*) in the UK. It holds the grant for the only Centre for Doctoral Training in energy demand. - is not sector-specific; it covers all energy uses and applies methods across sectors e.g. transport and buildings. - is managed as a coherent centre - this is facilitated by placing all staff under a single budget centre with a clear management structure. UCL-Energy is advised and guided by a prestigious International Advisory Board with CEOs and directors from leading companies around the world. - has leveraged a wide range of funding. From an initial UCL investment of £680k, it has so far raised £10m of external funding, including £2m from industry. - has strong leadership - its Director, Professor Tadj Oreszczyn has established a new academic department at UCL in less than 3 years, advises government at senior level, is on the boards of key organisations and has written several strategic papers on the future direction of energy demand research. - has critical mass and sustainability: UCL-Energy has 80 staff and PhD students