The project of the network IGNACE will be aiming at preparing an international research program on a new integrative treatment program for gambling disorders. The objective is to submit it to the H2020 Program on the topic "Societal Challenges - Personalised Medicine ", at the call SC1-PM-02-2017: New concepts in patient stratification. The desired amount of funding will be in the range of 5 to 6 Million Euros. The scientific objective of the research program that we would like to implement is to identify the profiles of patients most likely to respond to certain therapies compared to others, and to find potential treatment response markers. The final aim is to propose an “à la carte” care program tailor-made for each patient, which would have the best chance of success possible. The network constituted will be including renowned international scientists in the field of gambling from Europe, Australia and Canada, under the direction of a recognised French Team: the Addictology Department from the University Hospital of Nantes (Dr Marie GRALL-BRONNEC). The MRSEI funding will allow the network to: - Structure a new research network in the gambling field. - Conceptualize a coherent and relevant project for the SC1-PM-02-2017 H2020 call. It will bring a great added value to the project by allowing partners to establish a strong cohesion between them and by promoting multidisciplinarity, which could highly increase the chances of success for the H2020 call. - Ensure the project’s feasibility, thanks to the great research experience of each partner and the creation of a Methodological Support Unit. - Gather professionals working in very different fields around an integrative project, which will benefit from their various fields of expertise in order to achieve a common goal. In terms of technical and economic benefits, the research program designed by the network should eventually enable the development of a new treatment program, which would be marketed worldwide to help manage problem gamblers. Likewise, it integrates strong opportunities for SMEs to implement the technical aspects of the program (e.g., virtual reality or computerized assessment battery). The elaboration of the IGNACE network will help strengthen the French position in the international scientific landscape of gambling. The French coordinating team is already recognized for its national leadership position in the field of gambling, and the establishment of the network will be an opportunity to extend this leadership internationally. The overall program has a strong interdisciplinary and translational potential. Indeed, applying the concept and methods of stratified medicine in the field of gambling requires the participation of a wide range of disciplines (from fundamental disciplines such as neurobiology and genetics to more clinical disciplines such as therapies or behavioural assessment). The IGNACE group will thus propose an integrative program, combining a wide range of assessment techniques, therapeutic methods and response markers, so as to finally respond to 4 key points: 1/ Establishing a new treatment model using patient stratification to improve clinical decision-making. 2/ Transferring the research results to medical use, implementing a new treatment program. 3/ Increasing cost-effectiveness with more effective therapeutic strategies and a lower risk of relapse or of switching to other addictions. 4/ Increasing research and innovation opportunities for SMEs by including them in the implementation of the technical aspects of the treatment program.