The MAT4TREAT project consists in a consortium of 8 Universities, 5 of them European (UNITO, AAU, POLITO, UPV and UOI), and the other three from outside the EU (UNLP, McGill, SU), as well as two non academic institutions (ACEA and LQT). These groups are committed to work in the development of novel materials to be used in innovative integrated water tertiary treatments (to remove, for instance, Emerging Pollutants). This ambitious goal will be achieved by world leading research groups in the following fields: (i) graphene-based and other carbon-related materials, (ii) polymeric materials, (iii) oxidic ceramic materials, and (iv) hybrid inorganic-polymeric materials. The new materials will be used as adsorbents, as photocatalysts and as active layers for the fabrication of membranes, and thus tested for the pollutant removal from model aqueous solutions as well as from real water samples. Furthermore, approaches combining different materials and pollutant abatement technologies will be proposed and a demonstrative lab-bench apparatus for the integrated treatment of wastewaters will be built-up with the support of two European non academic institutions, which will directly participate to the project. Chemometric approach will be followed to optimize both materials production and experimental conditions for analytical purposes. Life Cycle Assessment of new materials and proposed technologies will be performed in order to evaluate their economic and environmental sustainability. For the implementation of the program secondments of ESRs and ERs are scheduled (95 secondments for 142 person-months) together with a diffusion plan to report on the obtained results, not only to the scientific community, but also to stakeholders and non-specialized audience.

CORNET is an ambitious project that develop a unique EU Open Innovation Environment (OIE), that cover the triangle of manufacturing, modelling and experimentation for the optimization the Organic/Large Area Electronic (OE) nanomaterials, materials behavior and nano-devices (OPVs, PPVs, OLEDs) manufacturing of R2R printing & gas transport (OVPD) processes, to validate materials models based on experimentation and fabricate tailored OE devices and systems for demonstration to industrial applications (e.g. automotive, greenhouses). CORNET will develop a sustainable OIE Platform and OIE Database for documentation of citable & industrially accepted protocols for OE material and device characterization, modelling and manufacturing. CORNET strategy will establish strong links and clustering with existing EU clusters (as EMMC, EMCC, EPPN), end-user & industrial associations, and EU networks to increase the speed of OE materials/device development and industry uptake, maximize the acceptance of the OIE and push-through standards for adoption by industry worldwide. The CORNET main objectives are to: 1. Develop an effective OIE with world-class experts in Manufacturing, Multiscale Characterization & Modelling, connected to EU clusters, and create a reliable database with citable protocols with contribution to Standards 2. Multiscale Characterization & Modelling to Optimize OE nanomaterials and devices fabrication and Models Validation 3. Optimize the nano-device Manufacturing of OPVs, PPVs, OLEDs by Printing (R2R, S2S) and OVPD Processes 4. Fabricate Tailored Devices, Systems and Demonstrate to industrial applications (e.g. automotive, greenhouses) CORNET has developed a strategic plan for the clustering activities with more than 800 existing related bodies, a Business Plan for the continuation of the OIE beyond the project and the Innovation Management, IPR and legal support services to protect generated foreground and to enable its adoption by the EU research & industrial communities.

Most older adults have multiple chronic diseases (multimorbidity) and multiple medications (polypharmacy). However, multimorbid patients are often excluded from clinical trials and most guidelines address diseases in isolation. Inappropriate drug prescription and poor drug compliance are common and contribute to up to 30% of hospital admissions. OPERAM investigators developed STOPP/START criteria to detect inappropriate drug use, both over- and underuse. Applying these criteria limits unnecessary polypharmacy and reduces underuse of indicated medications, but it remains uncertain whether systematic pharmacotherapy optimisation can improve clinical outcomes and reduce costs.We propose a multicentre randomised controlled trial to assess the impact of a userfriendly software-assisted intervention to optimise pharmacotherapy and to enhance compliance in 1900 multimorbid patients aged ≥75 years. Outcomes will include drug-related hospital admissions, health care utilisation, quality of life, patient preferences and cost-effectiveness. We will also perform several network meta-analyses (NMA) to provide new comparative evidence on the most effective and safest pharmacological and non-pharmacological interventions to reduce common causes of preventable hospital admissions (e.g. falls, fractures, bleeding). Therapy optimisation in the multimorbid elderly, enhanced compliance and discontinuation of less effective interventions have the potential to improve clinical, quality of life and safety outcomes, while reducing costs. We will provide a structured method with practical software solutions for optimal prescribing and new comparative evidence from NMAs for addressing multimorbidity and polypharmacy by means of customised, patient-centred guidelines. OPERAM ultimately aims at better healthcare delivery in primary and hospital care, based on effective, safe, personalised and cost-effective interventions that can be applied to the rapidly growing older population in Europe.

MUSICODE is an ambitious project which addresses the H2020 Call DT-NMBP-11-2020 “Open Innovation Platform for Materials Modelling” that will develop a novel Open Innovation Materials Modelling Platform to enable the Organic and Large Area Electronics Industry (OLAE) to expediate accurate and knowledgeable business decisions on materials design and processing for optimization of the efficiency and quality of OLAE device manufacture. This platform will integrate: (a) Material, process and device modelling with workflows spanning the micro-, meso- and macro- scales, validated by expert academic and industry partners. (b) Integrated data management and modelling framework with ontology-based semantic interoperability between scales, solvers, data and workflows, with industry-accepted material and process modelling parameters and protocols, employing graphical user interface tools for workflow design, analysis, optimization and decision making. (c) Plug-ins to Materials Modelling Marketplaces, Open Translation Environment, Business Decision Support Systems, etc. and to High Performance Computing infrastructures for workflow execution. The platform will demonstrate industry user case workflows to optimize OLAE materials selection & design as well as printing and gas-phase manufacturing. The MUSICODE Business Plan will ensure the platform sustainability, exploitation and industrial adoption beyond the project, with the ambition to become the central Open Innovation Hub for the OLAE industry and evolve as the central paradigm for cross-domain applications.