Recent events have demonstrated the need for readiness for medical supply and equipment rapid manufacturing repurposing. Eur3ka will deliver a trusted and unique capability to plug and collectively respond to a sudden demand increased in a coordinated and effective manner at unprecedented scale. Eur3ka mission is to bring together most recent R&I results in (1) Industry 4.0 standards, open automation modular manufacturing production line enablers; (2) industrial international common data space enablers and digital infrastructures; (3) global on-demand and manufacturing as a service platforms; (4) connected and smarter supply networks, and global medical supplies and equipment repositories; (5) the vibrant European and Global network of manufacturing DIH network innovation services and open experimental facilities. The main ambition of Eur3ka is to enable and facilitate global and fair access to (1) a Plug & Respond (P&R) repurposing resource coordination framework for pandemic crisis response, (2) a common open standardized modular manufacturing reference architecture and solutions, and (3) top digitally sovereign cross-sectorial manufacturing networks and capacities that should allow to connect global manufacturing and supply chain capabilities and medical knowledge on-demand and as-a-Service across the globe in an IP-responsive manner to ensure rapid manufacturing repurposing for an increased and sudden demand of medical supplies and equipment. Eur3ka builds and extends the existing Global Network of Advanced Manufacturing Hubs (AMHUBs) to leverage a comprehensive COVID response based on solid socio-tecno-economic pillars that bring together advanced manufacturing and digital enablers that will raise robustness, redundancy, resourcefulness, response, and recovery against current and future pandemics. Eur3ka vision builds on and accelerate current digital transformation industry 4.0 efforts, as well as flexible regulations and tailored workforce re-/up- skilling

Intensified continuous processes are a key innovation of the last decade for the production of high quality, high value and customer-specific products at competitive prices in a sustainable fashion. To realize the potential of this technology, key steps must be made towards long-term stable, tightly controlled and fully automated production. The goal of the CONSENS project is to advance the continuous production of high-value products meeting high quality demands in flexible intensified continuous plants by introducing novel online sensing equipment and closed-loop control of the key product parameters. CONSENS will focus on flexible continuous plants but the results will be transferable also to large-scale continuous processes. The research and development is driven by industrial case studies from three different areas, spanning the complete value chain of chemical production: complex organic synthesis, speciality polymers, and formulation of complex liquids. Innovative PAT technology will be developed for online concentration measurements (mid-resolution process NMR), for the online non-invasive measurement of rheological properties of complex fluids, and for continuous measurements of fouling in tubular reactors. New model-based adaptive control schemes based on innovative PAT technology will be developed. The project results will be validated in industrial pilot plants for all three types of processes, including validation in production containers that have been developed in the F3 Factory project. Further, methods for sensor failure monitoring, control performance monitoring and engineering support for PAT-based solutions will be developed. The exploitation of the new technologies will be facilitated by a tool for technology evaluation and economic impact assessment. A Cross-sectorial Advisory Board supports the transfer of PAT technologies and adaptive control to neighboring sectors of the European processing industry.