In contexts of crimes, disasters, terrorism or population displacement that presently occurs in Europe and numerous regions of the world, the necessity of having as soon as possible reliable, high throughput and real time analysis to identify individuals, victims and authors is a major societal and legal issue. The present MRSEI ForOnBoardLab project aspire to strengthen a multidisciplinary consortium which was federated, during a PhD thesis, around the theme of the rapid DNA analysis in the aim to structure a project for answering to the European H2020 call "SU-FCT02-2018-2019-2020: Technologies to enhance the fight against crime and terrorism, Sub-topic 1: [2019]; Trace qualification" at the beginning of 2019. The ambition of our European project is to set up a technological and normative European st of references, procedures and guidelines in the field of the genetic identification using high throughput DNA fingerprints, in real time and on site. In this way the project also aims at developing innovative biological collection devices and smart and on-board mobile laboratory in agreement with standards and reglementations and qualify and validated instruments and analytical methods. This in situ and real time forensic approach involves 9 academic, institutional and industrial partners from 6 European countries: France, Switzerland, Greece, Italy, Luxembourg, Belgium with intrernationaly recognized forensic leaders in DNA analysis performing more than 150 000 expertises by year. ForOnBoardLab aims to initiate and catalyse during 18 months the consortium to propose a structuring program in the H2020. Such a support of the French ANR within the framework of the AAP MRSEI will enhance the emergence of an European network in the field of biological sampling integrated into solutions of analysis high throughput , in situ and real time DNA including trainings and normative functions in a guides of recommanded practices to collect traces in complex crimes/disasters or major population migrations fields

The project aims to valorize the methane (CH4) contained in natural gas (NG) from restrained and localized sources which cannot be valorized into energy or chemical precursor for cost reasons. These NG emissions are thus released in atmosphere, flared or buried. The consortium proposes herein an eco-efficient bioprocess to convert the CH4 of these emissions into methanol in situ and in one step at a small scale. For this, an efficient bacterial catalyst will be implemented in a membrane reactor allowing safety, mass transfer efficiency, compactness and methanol recovery. To date, the biocatalyst allows methanol productions of 1 g/Lreactor/d (i.e. the oxidation of 0.7 LCH4/Lreactor/d) at 30°C and 1.1 bar, with water as sole by-product and a favorable carbon balance. This project intends to (i) increase the total turnover number (TTN) of the biocatalyst by genetic modifications and (ii) overcome the issue linked to the presence of ethane in NG.