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BindingDB Entry 50047697: Discovery of a Potent, Selective, Orally Bioavailable, and Efficacious Novel 2-(Pyrazol-4-ylamino)-pyrimidine Inhibitor of the Insulin-like Growth Factor-1 Receptor (IGF-1R).

Authors: BindingDB;

BindingDB Entry 50047697: Discovery of a Potent, Selective, Orally Bioavailable, and Efficacious Novel 2-(Pyrazol-4-ylamino)-pyrimidine Inhibitor of the Insulin-like Growth Factor-1 Receptor (IGF-1R).

Abstract

Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, CDK8/Cyclin C, Cyclin-dependent kinase, Cyclin-dependent kinase 1, Cyclin-dependent kinase 2, Cyclin-dependent kinase 9, Cytochrome P450 3A, Insulin-like growth factor I receptor, and MAP kinase ERK2, Uniprot P06493, P08069, P08684, P24941, P28482, P40989, P49336, P50613, and P50750

Keywords

1,3-beta-glucan synthase component GLS2, CDK8/Cyclin C, Cyclin-dependent kinase, Cyclin-dependent kinase 1, Cyclin-dependent kinase 2, Cyclin-dependent kinase 9, Cytochrome P450 3A, Insulin-like growth factor I receptor, and MAP kinase ERK2, AstraZeneca, Affinity

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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