BindingDB Entry 50042979: Fragment-based ligand design of novel potent inhibitors of tankyrases.

Name: BindingDB Entry 50042979: Fragment-based ligand design of novel potent inhibitors of tankyrases.
Creator: BindingDB
Keywords: Human diphtheria toxin-like ADP-ribosyltransferase (ARTD2 or PARP2), Human diphtheria toxin-like ADP-ribosyltransferase (ARTD3 or PARP3), Poly [ADP-ribose] polymerase 6, and poly-ADP-ribose polymerase 1 (PARP1), Nanyang Technological University, Affinity, 3. Good health

Research datakeyboard_double_arrow_right Dataset 01 Jan 2014 English Publisher:BindingDB

Authors: BindingDB;

doi: 10.7270/q23r0v82

BindingDB Entry 50042979: Fragment-based ligand design of novel potent inhibitors of tankyrases.

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Abstract

Small molecule binding data for protein Human diphtheria toxin-like ADP-ribosyltransferase (ARTD2 or PARP2), Human diphtheria toxin-like ADP-ribosyltransferase (ARTD3 or PARP3), Poly [ADP-ribose] polymerase 6, and poly-ADP-ribose polymerase 1 (PARP1), Uniprot P09874, Q2NL67, and Q9UGN5

Keywords

Human diphtheria toxin-like ADP-ribosyltransferase (ARTD2 or PARP2), Human diphtheria toxin-like ADP-ribosyltransferase (ARTD3 or PARP3), Poly [ADP-ribose] polymerase 6, and poly-ADP-ribose polymerase 1 (PARP1), Nanyang Technological University, Affinity

7 Research products, page 1 of 1

BindingDB Entry 50031961: Evolution of poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors. From concept to clinic.
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BindingDB Entry 8306: 3-phenyl-isoquinolin-1(2H)-one derivatives as PARP-1 inhibitors
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Fragment-Based Ligand Design of Novel Potent Inhibitors of Tankyrases
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BindingDB Entry 50042982: Discovery of novel, induced-pocket binding oxazolidinones as potent, selective, and orally bioavailable tankyrase inhibitors.
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BindingDB Entry 7027: 3-Oxo-2,3-dihydro-1H-indazole-4-carboxamide derivatives as PARP-1 inhibitors
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BindingDB Entry 50043370: Structure-efficiency relationship of [1,2,4]triazol-3-ylamines as novel nicotinamide isosteres that inhibit tankyrases.
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BindingDB Entry 50043451: TBA
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BindingDB Entry 50042979: Fragment-based ligand design of novel potent inhibitors of tankyrases.

BindingDB Entry 50042979: Fragment-based ligand design of novel potent inhibitors of tankyrases.

7 Research products, page 1 of 1

BindingDB Entry 50031961: Evolution of poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors. From concept to clinic.

BindingDB Entry 8306: 3-phenyl-isoquinolin-1(2H)-one derivatives as PARP-1 inhibitors

Fragment-Based Ligand Design of Novel Potent Inhibitors of Tankyrases

BindingDB Entry 50042982: Discovery of novel, induced-pocket binding oxazolidinones as potent, selective, and orally bioavailable tankyrase inhibitors.

BindingDB Entry 7027: 3-Oxo-2,3-dihydro-1H-indazole-4-carboxamide derivatives as PARP-1 inhibitors

BindingDB Entry 50043370: Structure-efficiency relationship of [1,2,4]triazol-3-ylamines as novel nicotinamide isosteres that inhibit tankyrases.

BindingDB Entry 50043451: TBA